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Dr. Makhluf J. Haddadin
Professor Organic Chemistry
B.Sc. (1957), MSc. (1959), American University of Beirut, Ph.D. (1962), University of Colorado, Boulder.
Office: Chemistry 418
Phone: 3987
E-mail: haddadin@aub.edu.lb
Personal Web Page
Research
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Heterocyclic Chemistry: Isobenzofurans, Isoindoles, Tetrazines, Quinoxaline 1,4-dioxides, Azacyanines with current interest in potential anti-tumor heterocycles.
Selected Publications
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Synthesis and Reactions of Heterocyclic Azacyanines, J. Org. Chem. 2001, 66, 1310 (with K. S. Huang, M. M. Olmstead and M. J. Kurth; Dedicated to Professor Costas H. Issidorides on the occasion of his eigthtieth birthday).
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Novel CFTR Chloride Channel Activators Identified by Screening of Combinatorial Libraries based on Flavone and Benzoquinolizinium Lead Compounds, J. Biol. Chem.2001, 276 (23), 19723, (with L.V.J. Gatietta, M.F. Springsteel, M. Eda, E.J. Niedzinski, K. By, M.J. Kurth, M.H. Nantz and A.S. Verkman).
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Imidazopyridinium and Pyridopyridinium Bromides: Synthesis and Hydrolysis, J. Org. Chem. 2002,67, 12382.
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Quinoxaline 1,4-dioxides: Hypoxia-Selective Therapeutic Agents, Molecular Carcinogensis, 2002, 33(4), 198 (with M. Assaf-Diab, P. Yared, C. Al- Assaad and H. U. Gali-Muhtasib).
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