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Nada M. Melhem, Assistant Professor
Medical Laboratory Sciences Program
Faculty of Health Sciences
American University of Beirut
Van Dyck Building
PO Box 11-0236
Beirut, Lebanon
Office: Room 325, Van Dyck
Tel: 961 1 350000 Ext. 4699; Fax: 961-1-744470
Email: melhemn@aub.edu.lb
Academic Degrees
PhD (2007) Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Research Interests
Cellular immunity to human immunodeficiency virus (HIV-1)
Dendritic cells and dynamics in viral infections
Hepatitis B virus: immunity and genetic correlates of protection
H1N1 flu
Research Projects
Affinity binding of HIV-1 peptides to T cells
Role of HLA and KIR as correlates of protection among HBV vaccinated and non-vaccinated individuals
Courses Taught
LABM 240: Clinical Bacteriology
EPHD 300: Principles of Epidemiology
EPHD 323: Epidemiology of Communicable and Non-Communicable Diseases
PBHL 398: Culminating experience
IDTH 206: Social and Preventive Medicine- Part 2
Selected Publications
Melhem, N; Yazbek, S; Ramia, S. "Hepatitis D in the Middle East and North Africa (MENA): Update." Current Hepatitis Reports 2012. 11 (4): 272-278
Ramia S; Melhem, NM; Kreidieh, K. "Hepatitis C virus infection in the Middle East and North Africa “MENA” region: injecting drug users (IDUs) an under-investigated population." Infection 2012. 40(1): 1-10.
Dergarabetian EM, Ghattass KI, El-Sitt SB, Al-Mismar RM, El-Baba CO, Itani WS, Melhem NM, El-Hajj HA, Bazarbachi AA, Schneider-Stock R, Gali-Muhtasib HU. "Thymoquinone induces apoptosis in malignant T –cells via generation of ROS." Front Biosci 2013. 5:706-719.
Colleton, BA, Huang, XL, Melhem, NM and Rinaldo, CR. Primary human immunodeficiency virus type 1-specific CD8+ T cell responses induced by myeloid dendritic cells . J Virol. 2009 83(12):6288-99.
Melhem, NM, Gleason, SM, Liu, X., and Barratt-Boyes, S. High-level antigen expression and sustained antigen presentation in dendritic cells nucleofected with wild –type viral mRNA but not DNA. Clin Vaccine Immunol 2008. 15(9):1337-44.
Melhem, NM, Liu, X., Boczkowski, D., Gilboa, E. and Barratt-Boyes, S. Robust CD4+ and CD8+ T cell responses to SIV using mRNA-transfected dendritic cells expressing lysosome-targeted antigen from infected monkeys. Eur J Immunol 2007. 37(8):2164-73.
Barratt-Boyes SM, Brown KN, Melhem NM, Soloff AC, Gleason SM. Understanding and exploiting dendritic cells in human immunodeficiency virus infection using the nonhuman primate model. I mmunol Res. 2006; 36 (1-3):265-74.
Professional Affiliations
American Association of Immunologists
WHO-EMRO Temporary advisor
WHO Epidemiological Working Group on H1N1 (member)
National Committee of Communicable Diseases (member)
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