CCECS plays a leading role in empowering the most vulnerable populations through high impact multi-year interventions, by first identifying themes, setting the roadmap for project development, and establishing strategic partnerships with academia, stakeholders, and funding agencies. Each contextualized SCI is initially a prototype that is meticulously designed to tackle local complexities; it must be flexible, resilient, and positioned in the most appropriate setup for it to thrive. Insights, common practices, and readily available resources within the targeted communities provide invaluable building blocks that increase local buy-in, ownership, and the sustainability of the prototype. Leveraging cutting-edge operational research, SCIs yield tangible solutions that are expandable to cover a wider scope of the same targeted community and are transferable to various locations enduring similar challenges.