Dean Rabi Mohtar participated in the American Association for the Advancement of Science (AAAS)’s Annual Meeting on February 2018, in Austin, Texas, under the theme “Science Transcending Boundaries”, where he presented an overview of the system-of-systems Water-Energy-Food (WEF) Nexus. He emphasized that communities can change behaviors to address complex challenges within the WEF Nexus using dialogue that grows out of the data and analytics of the WEF systems. A holistic system-of-systems platform that quantifies the interlinkages between these three primary resources assists in the identification of hotspots, enabling the evaluation of levers and identification of potential interventions toward sustainable management of these resources. Building disciplinary sciences and knowledge in conservation and management, this platform produces the data to understand the tradeoffs and can then be used as a catalyst for dialogue between stakeholders from all backgrounds and sectors of society to foster the needed behavioral changes across the nexus. Using specific applications from Texas to address the predicted water gap, Dr. Mohtar presented tools for sustainable energy production, and concluded with insights on nexus applications that can be generalized across thematic and regional applications in the near future. AAAS plans to formulate a new communication initiative that will highlight ways in which communities are actively and effectively responding to climate change at the local, state and regional levels. This will include the critical role of science. “How We Respond” is one of the new initiatives based on previous AAAS communication activities and will significantly contribute to and expand ongoing discussion and responses to climate change.