American Univesity of Beirut

Effect of adoptive T cell therapy on VEGF signaling pathway in DMH-Induced colon cancer in balb/c mice

​​​Colon cancer is the fourth most leading causes of cancer-related deaths worldwide accounting for nearly 7-10% of all cancers. Colon cancer treatment remains challenging especially that chemotherapy results in adverse outcomes on patients’ health. Adoptive T Cell Therapy (ACT) is a new type of immunotherapy that relies on isolating, culturing and re-injecting patients’ own CD8 T cells. This is the first study to determine the effect of ACT alone or in adjunct to Sorafenib on the Vascular Endothelial Growth Factor (VEGF) signaling pathway in DMH-induced colon cancer in Balb/c mice.

To read the full study, please CLICK HERE.​

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