Lab of Dr. Aida Habib

​​​​​​​​​​​​​​​​​​​​​​​​​​​​Link to Dr.Habib​'s​ FMIS Profile ​

​​​​​Research Area​

Mechanisms in inflammation and vascular biology

Research Projects

  • Lipid mediators, arachidonic acid metabolites in inflammation and Liver fibrosis
  • Vascular reactivity, autophagy and statins
  • Cyclooxygenase inhibitors, statins and analogues of fenoprofen and benzofuran in inflammation
  • Platelet activation and Cyclooxygenase inhibitors​

Selected Publications

Statins Modulate Cyclooxygenase-2 And Microsomal Prostaglandin E Synthase-1 In Human Hepatic Myofibroblasts.
Mouawad CA, Mrad MF, El-Achkar GA, Abdul-Sater A, Nemer GM, Creminon C, Lotersztajn S, Habib A.
Journal of Cellular Biochemistry. 2016, vol.117, no.5, pp-1176-86

Thiazole derivatives as inhibitors of cyclooxygenases in vitro and in vivo.
El-Achkar GA, Jouni M, Mrad MF, Hirz T, El Hachem N, Khalaf A, Hammoud S, Fayyad-Kazan H, Eid AA, Badran B, Merhi RA, Hachem A, Hamade E, Habib A.
Eur J Pharmacol. 750 :66 (2015)

Statins upregulation of heme-oxygenase-1 in macrophages involves nitric oxide synthase, p38 MAPK and C/EBP and AP-1 transcription factor activation.
Mouawad, C., Mrad, M., Al-Hariri, MA, Soussi, H., Hamade E., Alam, J. Habib A.
PLoS One, May 22;8(5):e64092, (2013)

Statins Modulate Transcriptional Activity Of Heme-Oxygenase-1 Promoter In NIH 3T3 Cells.
Mrad M.F., Mouawad C.A., Al-Hariri M., Eid A.A., Alam J., Habib A.
PLoS One, May 22;8(5):e64092, (2013)

New analogues of 13-hydroxy-octadecadienoic acid and 12-hydroxyeicosatetraenoic acid block human blood platelet aggregation and cyclooxygenase-1 activity.
Hirz , T. , Khalaf, A., El-Hachem, N., Mrad, M.F., Abdallah, H., Créminon, C., Grée, R., Abou Merhi , R., Habib A. , Hachem, A., and Hamade, E.
Chem Cent J., 6(1):152 (2012)

Characterization And Assessment Of Potential Micrornas Involved In Phosphate-Induced Aortic Calcification.
Fakhry M, Skafi N, Fayyad-Kazan M, Kobeissy F, Hamade E, Mebarek S, Habib A, Borghol N, Zeidan A, Magne D, Fayyad-Kazan H, Badran B. ​
Journal Of Cellular Physiology, 2018 May;233(5):4056-4067

In Vivo Platelet Activation And Aspirin Responsiveness In Type 1 Diabetes.
Zaccardi F, Rizzi A, Petrucci G, Ciaffardini F, Tanese L, Pagliaccia F, Cavalca V, Ciminello A, Habib A, Squellerio I, Rizzo P, Tremoli E, Rocca B, Pitocco D, Patrono C. ​
Diabetes. 2016, vol.65, no.2, pp-503-9

Patient-Independent Variables Affecting The Assessment Of Aspirin Responsiveness By Serum Thromboxane Measurement.
FPetrucci G, Rizzi A, Cavalca V, Habib A, Pitocco D, Veglia F, Ranalli P, Zaccardi F, Pagliaccia F, Tremoli E, Patrono C, Rocca B ​
Thrombosis And Haemostasis. 2016, vol.116, no.4​​