Lab of Dr. Margret Shirinian

Main Links
- About AUB
  About AUB
  
  Founded in 1866, the American University of Beirut is a teaching-centered research university based on the American liberal arts model of higher education. AUB has over 8,000 students and 800 faculty members. The University encourages freedom of thought and expression and seeks to graduate men and women committed to creative and critical thinking, lifelong learning, personal integrity, civic responsibility, and leadership.
- Academics
  Academics
  
  AUB is accredited in the US by the Middle States Commission on Higher Education and includes six faculties: Arts and Sciences, Medicine, Engineering and Architecture, Agricultural and Food Sciences, Health Sciences, and Business. AUB offers more than 130 programs leading to bachelor's, master's, MD, and PhD degrees. The main language of instruction is English.
- Admissions
  Admissions
  
  Learn more about how you can join the American University of Beirut. AUB seeks applicants with a proven record of academic excellence, intellectual vitality, and civic responsibility. In accordance with its founding mission and its equal opportunity policy, the University admits students regardless of race, color, religion, gender, age, disability, or nationality.
- Research
  Research
  
  The vibrant and dynamic research environment at AUB enhances the educational experience for all and serves the wider communities—local and global—by advancing knowledge in a wide range of disciplines.
- Outreach
  Outreach
  
  Recognizing and honoring our responsibility for others has been an integral part of AUB’s mission since the earliest days. Today, AUB is at the forefront of addressing the most pressing concerns of this country, this region, and its people.
- Boldly Campaign
  BOLDLY Campaign
  
  To ensure the University can continue to inspire current and future generations of smart and able students who can rise to this challenge, we are embarking on a transformative capital campaign, BOLDLY AUB: The Campaign to Lead, Innovate, and Serve.
AUB Community
- A - Z
- Find People
- Libraries
- Alumni
Public
- Telehealth
- AUBMC
- Give
Useful Tools
- E-learning
- AUBSIS
- Webmail
- Title IX Online Training

Lab of Dr. Margret Shirinian

HomeCurrently selected
About Us
- Chairperson’s Welcome Message
- History
Directory
- Faculty Members
- Staff
Educational Programs
Research Activities
Recent
Contact Us

Link to Dr.Shirinian's FMIS Profile

Research Area

Genetics (Drosophila melanogaster), Epigenetics, Cancer, Molecular Biology

Research Projects

Epigenetics in development and disease

Role of Drosophila dTet in brain development
Role of TET proteins in development and disease
Role of oncohistones in development and cancer

Research Personnel Supervised

Name: Felice Frey Position: Post-doctoral fellow Email: ff27@aub.edu.lb Phone extension: 5126	Name: Joy Ismail Position: PhD candidate Email: jni00@aub.edu.lb Phone extension: 5126
Name: Mirna Ghannam Position: Research assistant Email: mg84@aub.edu.lb Phone extension: 5126	Name: Amani Al Outa Position: PhD candidate Email: aya11@mail.aub.edu Phone extension: 5126
Name: Joelle Mady Position: Masters Student Email: jrm06@mail.aub.edu Phone extension: 5126	Name: Dana Abubaker Position: Masters Student Email: dma70@mail.aub.edu Phone extension: 5126

Selected Publications

Drosophila Tet is expressed in midline glia and is required for proper axonal development.

Ismail N J, Badini S, Frey, F, Abou-Kheir W, Shirinian M.

Frontiers in Cellular Neuroscience. 2019

Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness.

Boileau M*, Shirinian M*, Gayden T*, Harutyunyan A, Chen C, Mikael L, Duncan H,Neumann A, Arreba-Tutusaus P, De Jay N, Zeinieh M, Rossokhata K, Zhang Y, Nikbakht H, Mouawad C, Massoud R, Frey F, Nasr R, El Cheikh J, El Sabban M, Kleinman C, Mahfouz R, Minden M, Jabado N**, Bazarbachi A**, Eppert K**.

Nature Communications. 2019

Validation Of A Drosophila Model Of Wild Type And T315i Mutated Bcr-Abl1 In Chronic Myeloid Leukemia: An Effective Platform For Treatment Screening.

Al Outa A, Abubaker D, Bazarbachi A, El Sabban M, Shirinian M*, Nasr R*

Haematologica. 2019

Identification Of Genes Functionally Involved In The Detrimental Effects Of Mutant Histone H3.3-K27m In Drosophila Melanogaster.

Berlandi J, Chaouch A, De Jay N, Tegeder I, Thiel K, Shirinian M, Kleinman CL, Jeibmann A, Lasko P, Jabado N, Hasselblatt M

Neuro-Oncology. 2019

The Htlv-1 Oncoprotein Tax Is Modified By The Ubiquitin Related Modifier 1 (Urm1).

Hleihel R, Khoshnood B, Dacklin I, Omran H, Mouawad C, Dassouki Z, El-Sabban M, Shirinian M*, Grabbe C*, Bazarbachi A*

Retrovirology. 2018

Contact Us

For various questions, please try contacting us via social media first!
read more

Privacy Statement

We take data privacy seriously and adhere to all applicable data privacy laws and regulations.
read more

Copyright and Disclaimer

Written permission is needed to copy or disseminate all or part of the materials on the AUB website.
read more

Title IX, Non-Discrimination, and Anti-Discriminatory Harassment

AUB is committed to providing a safe, respectful, and inclusive environment to all members of its community.
read more

American University of Beirut