Link to
Dr.Massaad's FMIS Profile
Research Area
Immunology/Primary Immunodeficiency
Research Projects
Functional and Genetic study of Primary Immunodeficiency Patients
Selected Publications
A peptide derived from the Wiskott-Aldrich syndrome (WAS) protein-interacting protein (WIP) restores WAS protein level and actin cytoskeleton reorganization in lymphocytes from patients with WAS mutations that disrupt WIP binding
Massaad M.J.*,Ramesh N., Le Bras S., Giliani S., Notarangelo L., Al-Herz W., Notarangelo LD, Geha R.S.
Journal of Allergy and Clinical Immunology. Apr;127(4):998-1005.e1-2. PMID: 21376381
Binding of WIP to actin is essential for T cell actin cytoskeleton integrity and tissue homing
Massaad M.J., Oyoshi MK, Kane J, Koduru S, Alcaide P, Nakamura F, Ramesh N, Luscinskas FW, Hartwig J, and Geha RS
Molecular and Cellular Biology. Dec 1;34(23):4343-54
Autoimmune lymphoproliferative syndrome caused by a homozygous FasL mutation that disrupts FasL assembly
Sobh A., Crestani E., Cangemi B., Kane J., Chou J., Pai SY., Notarangelo LD., Al-Herz W., Geha R.S.*,
Massaad M.J.*
Journal of Allergy and Clinical Immunology. October 9. pii: S0091-6749(15)01249-X
Chronic mucocutaneous candidiasis associated with an SH2 domain gain of function mutation that enhances STAT1 phosphorylation
Sobh A., Chou J., Schneider L., Geha R
Massaad M.J.*
Journal of Allergy and Clinical Immunology. Feb 29. pii: S0091-6749(16)00131-7
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity
Massaad M.J.*, Zhou J, Tsuchimoto D, Chou J, Jabara H, Janssen E, Glauzy S, Olson BG, Morbach H, Ohsumi TK, Schmitz K, Kyriacos M, Kane J, Torisu K, Nakabeppu Y, Notarangelo LD, Chouery E, Megarbane A, Kang PB, Al-Idrissi E, Aldhekri H, Meffre E, Mizui M, Tsokos GC, Manis JP, Al-Herz W, Wallace SS, Geha RS
Journal of Clinical Investigation. Nov 1;126(11):4219-4236
Awards
2014-2019
| Boston Children’s Hospital Investigatorship Award
|
2014
| Best Poster Award at the European Society for Immunodeficiencies
|
2007
| Paul A. Dobuler Prize for “Excellence in Immunodeficiency Research”
|
2001-2002
| McGill Faculty of Graduate Studies Scholarship
|
1999-2003
| McGill Faculty of Medicine Scholarship
|
| 1997-1998 | FCAR McGill Cancer Centre Scholarship |
| 1999, 2000 | Canderel Travel Award, McGill Cancer Centre |
| 1998 | McKinnell Travel Award, McGill University |
| 1993-1996 | Biology Department Scholarship |
1988-1992
| Hariri Foundation Scholarship |