Lab of Dr. Samia Khoury

​​​​​​​​​​​​​​​​​​​​​​​​​Link to Dr.Khoury's​​ FMIS Profile

​​​​​​​​​​​​​​​​​​​Rese​arch Area

 ​Neuroimmunology, Multiple sclerosis, traumatic brain injury​

​​​​​​​​​​​​​Research P​rojects

  • Exosomal microRNAs in Multiple Sclerosis: Reconciling expression signatures with disease relapse, remission, and response to treatment
  • Comprehensive Multiple Sclerosis Database (AMIR)
  • Cerebrospinal fluid, Urinary and Plasma biomarkers in Multiple Sclerosis
  • Immunological Pattern During Multiple Sclerosis Relapses and Response to Treatment
  • Correlation between Retinal Optical Coherence Tomography Measures and Cognitive/Physical Disability in Patients with Early Multiple Sclerosis: a prospective study​
  • EBV Infected B Lymphocyte Exosomes and Dendritic Cells: Differential Cytokine Profile in Multiple Sclerosis Selected Publications

Selected Publications

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
Starossom SC, Garcia JC, Woelfle T, Romero-Suarez S, Olah M, Watanabe F, Cao L, Yeste A, Tukker JJ, Quintana FJ, Imitola J, Witzel F, Schmitz D, Morkel M, Paul F, Infante-Duarte C, Khoury SJ
Nat Comm 2019; 10:1-14. doi: 10.1038/s41467-018-08140-7

Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance
Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E
J Immunol 2019; 202: . doi: 10.4049/jimmunol.1801425

Identification of MS-specific serum miRNAs in an international multicenter study
Regev K , Healy BC, Paul, A, Diaz-Cruz C, Mazzola MA, Raheja R, Glanz BI, Kivis ̈akk P, Chitnis T, Jagodic M, Piehl, F, Olsson F, Khademi M, Hauser S, Oksenberg J , Khoury SJ, Weiner HL , and Gandhi R. 
Neurol Neuroimmunol Neuroinflamm 2018;5:e491. PMC6117192. doi:10.1212/NXI.0000000000000491 

The Bayesian risk estimate at onset (BREMSO) correlates with cognitive and physical disability in patients with early multiple sclerosis
Said M, El Ayoubi N, Hannoun S, Haddad R, Saba L, Jalkh Y, Yamout BI, Khoury SJ
Multiple Sclerosis and Related Disorders 2018; 26:96-102. doi: 10.1016/j.msard.2018.09.003

Efficacy and safety of natalizumab extended interval dosing​
Yamout BI, Sahraian MA, Ayoubi El N, Tamim H, Nicolas J, Khoury SJ, Zeineddine M. 
Multiple Sclerosis and Related Disorders 2018; Jul 5;24:113–6. doi: 10.1016/j.msard.2018.06.015

Gadolinium Effect on Thalamus and Whole Brain Tissue Segmentation in Multiple Sclerosis
Hannoun S, Baalbaki M, Haddad R, Saaybi S, El AyoubI NK, Yamout BI, Khoury SJ, Hourani R
Neuroradiol 2018; 60(11); 1167-1173. doi: 10.1007/s00234-018-2082-5

Effectiveness of alternative dose fingolimod for multiple sclerosis
Longbrake EE, Kantor D, Pawate S, Bradshaw MJ, von Geldern G, MD, Chahin S, Cross AH, Parks BJ, Rice M, Khoury SJ, Yamout B, Zeineddine M, Russell-Giller S, Caminero-Rodriguez A, Edwards K, Lathi E, VanderKodde D, Meador W, Berkovich R, Ge L, Bacon TE, Kister I
Neurology: Clinical Practice 2018:8;1-6. PMC5914753. doi:10.1212

Foxo1 Promotes Th9 Cell Differentiation and Airway Allergy​
Buttrick T, Wang W, Yung C, Trieu K, Patel K, Khoury SJ, Ai X, Elyaman W
Sci Reports 2018; 8:818. PMC5770389. doi: 10.1080/21541248.2017.1341365


Research Grants​

​​​Tit​l​e:Microglial activation and neural stem cells cross talk post
Role: Principal In​vestigator
Source: ONR
Year: 2017 ​– 2019​ ​
​​​​​Tit​l​e:EBV Infected B Lymphocyte Exosomes and Dendritic Cells: Differential Cytokine Profile in Multiple Sclerosis​
Role: Principal Investigator
Source: Lebanese National Council for Scientific Research
Year: 2016 – 2018​

Awards

198​4​​Alpha Omega Alpha Society
​​The Alpha Omega Alpha Honor Medical ​
2002
​Elected member
American Society of Clinical Investigation
2002
​Elected member
​American Neurological Association
2007
​Kuwait Prize for Immunolog​y 
Kuwait Foundation for the Advancement of Sciences
2009
​Jack, Sadie and David Breakstone Chair
Harvard Medical School
2011
​Elected Fellow
American Academy of Neurology
2011
​Gold Award
Medical Alumni of the American Univ of Beirut
2012
​Excellence in Science Award
Lebanese Society for the Advancement of Science
2013
​Elected Fellow
Royal College of Physician-England
2013
​Elected Fellow 
American Neurological Association
2017
​Research Excellence Award
CNRS, Lebanon
2017
​Innovative Doctors
Saudi Arabia Embassy​​
​ ​