The Bone Marrow Transplantation (BMT) team at the American University of Beirut Medical Center (AUBMC) is committed to providing high-quality, compassionate, and state-of-the-art care. We shall make every effort to utilize the transplantation-based therapies and expertise to serve your personalized needs to eliminate cancer. Our program has a strong dedication to clinical and basic science research and to advancing the field of BMT.
The AUBMC BMT program saw fruition in July 2004 with the opening of a dedicated BMT unit. The program is currently the pioneering transplant program in Lebanon and is witnessing an unprecedented growth (45 transplants in 2011, 103 transplants in 2016 including 52 allogeneic BMT). It is also the first to perform unrelated donor transplant, mismatch and haplo-identical transplant in Lebanon. Our center attracts patients from Lebanon and the region. The program also participates in transplant research and is an active member of the European (EBMT) and Eastern Mediterranean (EMBMT) Bone Marrow Transplantation groups. Outcome results from AUBMC BMT program bench-mark with the most prestigious BMT programs in North America and Western Europe. The program received the JACIE accreditation in 2016, being the only internationally accredited program in Lebanon and one of eight worldwide outside Europe and North America.
Ali Bazarbachi, MD, PhD
Professor of Medicine
Director, BMT Program
American University of Beirut Medical Center
Why Choose BMT at AUBMC?
Medical centers that offer bone marrow transplantation (BMT) services are increasing, and this makes deciding where to seek BMT therapies more difficult. Here are some reasons why the American University of Beirut Medical Center (AUBMC) is your best hope for BMT.
- The AUBMC BMT program is an official member (number CIC369) of the European Blood and Marrow Transplantation Group (EBMT).
- The program received the prestigious JACIE accreditation in 2016, being the only internationally accredited program in Lebanon and one of eight worldwide outside Europe and North America.
- The program is currently the pioneering transplant program in Lebanon and is witnessing an unprecedented growth (45 transplants in 2011, 103 transplants in 2016 including 52 allogeneic BMT).
- The program is the first to perform unrelated donor transplant, mismatch and haplo-identical transplant in Lebanon.
- We use and develop front-line diagnostic technology. That helps physicians pinpoint each patient's unique needs and tailor treatment for best possible outcome.
- Our group of specialized nurses are properly trained in BMT care in order to provide patients with the utmost attention and quality care.
The BMT Program is well-recognized nationally and internationally for its cutting-edge basic, clinical, and translational cancer research, particularly in the field of hematological malignancies. The research activities focus on developing targeted therapies for human leukemia. Research results were published in leading scientific journals, including "The New England Journal of Medicine", "Science", "The Lancet Oncology", "Blood", and "Cancer Research".
The type of bone marrow donation determines the type of transplantation.
- Allogeneic Transplantation: The person giving the bone marrow or stem cells is a genetically-matched family member, usually a brother or sister.
- Unrelated Allogeneic Transplantation (MUD): The person donating marrow is unrelated to the patient. Chances of finding an unrelated compatible donor from the general population depends on the uniqueness of tissue type.
- Syngeneic Transplantation: The person donating the bone marrow or stem cells is an identical twin.
- Autologous Transplantation: The patient donates her/his own bone marrow or stem cells prior to treatment for re-infusion later.
When the patient is diagnosed to have leukemia, aplastic anemia, and some lymphomas, it becomes crucial to replace the unhealthy marrow with a healthy one. Allogeneic, unrelated, and syngeneic bone marrow transplantations (BMT's) are most commonly used in persons with those diseases. While in lymphomas and multiple myeloma, an autologous BMT is usually done.
This is a pictorial guide to the steps involved in undergoing autologous BMT. It is designed to give patients, their families, and their friends a better understanding of the steps involved in a BMT.
There are generally three steps in undergoing autologous BMT
- Receiving chemotherapy to reduce any cancer cells in the body to a minimum
- Collection and storage of bone marrow cells
- Transplantation involving high doses of chemotherapy with or without radiation, re-infusing the stem cells and then, waiting for the bone marrow function to return
Bone Marrow Transplantation Stages